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Angiogenesis in Kidney Cancer
Most cases of kidney cancer are driven by mutations in a gene that regulates the amount of oxygen available to tissues. These genetic mutations promote cancer cells to divide uncontrollably and also stimulate the growth of blood vessels, a process called angiogenesis. Cancerous tumors in the kidney require a blood supply to provide oxygen and nutrients. Proteins called growth factors that are produced by cancer cells instruct capillary blood vessels to grow and migrate towards the tumor.


Last updated May 29, 2011